SkyScan 1276 - System specifications

*SkyScan 1276*

SkyScan 1276

X-ray source

  • Type: Tungsten source

  • Adjustable output: power Up to 20W and voltage between 40–100 kV

  • Spot size: < 5 µm at 4 W

  • Automated 6-position filter changer: no filter, Al 0.25mm, Al 0.5mm, Al 1mm, Al 1mm +Cu 0.03mm, low dose (dose reducing filter)

X-ray detector

  • Sensor type: 16 megapixels cooled CMOS camera with coupling to scintillator by 1.8:1 fiber optic taper

  • Sensor dimensions: 4096 × 4096 pixels

  • Pixel size: 2.8 µm to 75 µm

  • Spatial resolution: 6 µm

  • Sensor binning: up to 8x (512 x 512 pixels)

  • Capability: Wide scan mode for large object

  • Readout rate: 4 frames/s full format and17 frames/s at 8x8 binning

Imaging chamber

  • Temperature-controlled platform for maintaining physiological conditions

  • Integrated gas anesthesia system

  • Radiation Shielding: fully enclosed X-ray-safe chamber

  • Live Animal Monitoring: 5 MP color visible-light camera for real-time monitoring

  • Respiratory monitoring with breathing detection

  • Object capacity: up to 310 mm height and 75 mm diameter

Rotation mechanics

  • Adjustable rotation steps: from 0.1 to 1° steps

  • Rotation range: 180 and 360° option

Software suite

  • SkyScan 1276 - data acquisition platform

  • NRecon - reconstruction and pre-processing

  • Dataviewer - Slice-by-slice inspection and registration tools

  • CTVox - High-quality volume rendering

  • CTAn - Advanced 2D/3D image analysis & quantification

  • CTVol - Surface model visualization and export (CAD/3D printing)

Available accessories

  • Hydroxyapatite phantoms for BMD calibration with a 2-32 mm diameter range

  • QRM phantom for spatial resolution calibration

  • Measurements calibration in Hounsfield Units (HU)

  • ECG patches for cardiac gating and physiological monitoring during in vivo imaging

  • Real-time dose meter inside chamber for dose tracking

  • Imaging cassettes of various diameters to accommodate ex vivo samples and whole-body scans of mouse and rats with optimized specimen positioning

Operational protocols and risk assessments

The SOPs and RAs related to the use of the SkyScan 1276 system are available https://drive.google.com/drive/u/1/folders/1ZRjqZFXyPtIG-4KglzBfxUvnnrdUHj9P, upon request. These documents are stored in the designated folder and include:

  • SkyScan 1276 user manual

  • Radiation safety program manual

  • SkyScan 1276 workflow

  • SOP for SkyScan 1276 utilization

  • RA for SkyScan 1276 with anesthesia

  • Bruker useful information