SkyScan 1276 - Main applications

The main application of the SkyScan 1276 is non-invasive in vivo micro-computed tomography (microCT) imaging for visualizing anatomical structures in small animal models with high spatial resolution. Its ability to capture detailed 3D images of bone and soft tissue, combined with fast scanning speeds and low radiation doses, makes it especially powerful for longitudinal studies of disease progression, treatment response, and physiological changes over time in live animals.

In vivo microCT imaging

*Common applications of in vivo microCT*

Common applications of in vivo microCT

Here are common applications of in vivo microCT imaging:

  • Bone morphometry

    • Analysis of bone microarchitecture and bone mineral density (BMD)

    • Studies of osteoporosis, bone healing, growth, and regeneration

  • Lung imaging

    • Functional respiratory analysis using respiratory gating (4D microCT)

    • Monitoring pulmonary disease progression (fibrosis, emphysema, tumor, tuberculosis)

  • Body composition analysis

    • Quantification of adipose tissue

    • Quantification of muscular tissue

  • Biomaterial implant evaluation

    • Assessment of biocompatibility, structural integrity, and stability of implants

  • Soft tissue visualization (contrast agent)

    • Morphological and structural analysis of liver, spleen, and kidneys

    • Volumetric analysis of soft tissue organs

  • Cancer research (contrast agent)

    • Monitoring tumor growth, localization, and vascularization

    • Evaluating efficacy of anti-cancer therapies

  • Cardiac imaging (contrast agent)

    • Functional cardiac analysis with cardiac gating (4D microCT)

    • Tracking cardiovascular disease progression (atherosclerosis, aneurysms, stroke)

  • Vascular imaging (contrast agent)

    • 3D mapping and quantification of blood vessels and vascular networks

Additional microCT applications

*Common applications of microCT for biological and material science*

Common applications of microCT for biological and material science

Here are some biological research applications of microCT imaging:

  • Hard tissue micro-architecture

    • Comparative anatomy studies

    • Dental structure and development

    • Aging-related skeletal changes

  • Invertebrate imaging

    • Visualization of exoskeletons, flight apparatus, shells, and gills

  • Contrast-enhanced soft tissue imaging

    • High-resolution visualization of internal organ structures

  • Plant biology

    • Seed morphology and development

    • Root system architecture

    • Leaf anatomy and venation patterns